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60 Days Supply

GMP Cert.

3rd Party Tested

Pure Fisetin Supplement ∘ 400mg per serving

Name: Pure Fisetin
SKU: MP-FST-C-060-B
Price: 84.0 USD
Availability: InStock

Brain Health

Longevity

Heart Health

Some cells stop working but refuse to leave. They sit inside your body causing inflammation and accelerate how you age. Pure Fisetin helps flush them out

Accreditations

Ultra pure, high-grade ingredients only Naturally sourcedClinical-strength daily doseMicronised for maximum absorbencyLab-grade, UV safe amber glass vessel

What is Pure Fisetin?

Fisetin is a naturally occurring flavonoid, a group of plant compounds with antioxidant properties found in small amounts in fruits, vegetables, tea and chocolate. It is found in strawberries and asparagus and is known for its anti-ageing properties. Studies have shown fisetin can extend lifespan in yeast, worms, flies and mice. It acts as a senolytic, helping to clear senescent ("zombie") cells, which accumulate with age and contribute to inflammation and tissue dysfunction. By reducing these cells, fisetin may help support healthy ageing.

Benefits & Why it Works

✓ Supports your body's cellular clean-up processes

✓ Fights inflammation

✓ Promotes healthy aging & longevity

✓ Supports brain health, memory, and focus

✓ Supports heart & blood vessel health

How quickly will I see results with Pure Fisetin?

Studies show senescent cell biomarkers typically improve after 2-8 weeks of supplementation.

Ingredients & Source

Contains 60 capsules. One capsule contains 400mg of Pure Fisetin.

The capsule shell is made from 100% vegetable cellulose.

Vegan and Vegetarian
Gluten Free
Non-GMO
Allergen Free
Halal / Kosher Friendly

Purity and Third Party Testing

Manapura's current batch of Pure Fisetin has been third-party tested by an independent laboratory, and shown to be 100.00% pure.

View the certificate in our Trust Centre →

How to Take Pure Fisetin

For maximum effectiveness, take one capsule daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Fisetin can be taken at any time of day; however, taking it at the same time every day is recommended.

Precautions

This product is intended for use by healthy adults only. Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

Shipping & Delivery

UK ORDERS:

Standard Delivery (FREE):Delivered via Royal Mail 48H service.
Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.

Manapura delivers pure Fisetin, extracted from plants and clinically researched to support cellular health, anti-ageing, and reduced Inflammation

Ultra Pure

Extracted naturally - with absolutely no synthetic additives or fillers

Medical Grade

We make our supplements in certified facilities (cGMP & ISO 9001) the same standards used for best-in-class pharmaceuticals.

Micronised For Maximum Absorption

Our formulas are processed into tiny particles (micronised) so your body can absorb it more easily.

Vegan & Gluten-Free

Purposefully suitable for most diets, our zero-tolerance for additives gives you the cleanest form that the body recognises and can absorb.

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Guidance

For maximum effectiveness, take one capsule daily with a meal for optimal absorption. For best results, complement your routine with a balanced diet rich in healthy fats.

Fisetin can be taken at any time of day; however, taking it at the same time every day is recommended.

Dosage

Store in a cool, dry place. Keep away from extreme heat and direct sunlight. Reseal container after each use. Keep out of reach of children.

Storage

This product is intended for use by healthy adults only. Do not take if you are pregnant, breastfeeding, or using anticoagulant or antiplatelet medications—for example, warfarin (Coumadin), heparin, aspirin, or clopidogrel (Plavix)—which are typically prescribed to individuals with cardiovascular or clotting concerns.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

Precautions

Pure Fisetin Supplement FAQs

What is fisetin and what are its benefits?

Fisetin is a natural flavonoid found in strawberries, apples and the smoke tree. It's best known as a senolytic: it helps clear senescent ('zombie') cells that build up with age and drive inflammation. That's why it's one of the most exciting compounds in longevity research.

How long do I need to supplement for to achieve the benefits?

Studies show senescent cell biomarkers typically improve after 2-8 weeks of supplementation.

Is Fisetin safe to take?

Yes. Research suggests that Fisetin supplementation is well-tolerated.

What is a senolytic, and why does it matter?

Senolytics are compounds that help the body clear senescent cells: ageing 'zombie' cells that stop dividing but stay in your tissues, releasing inflammatory signals. Clearing them supports healthier tissues as you age, and fisetin is one of the most studied natural senolytics.

How quickly does Fisetin start working?

Fisetin works at a cellular level, so its benefits build over time. Studies typically measure changes after 2 to 8 weeks of daily use, so take it consistently.

When should I take Fisetin?

Take 1 capsule per day with a source of fat, such as nuts or olive oil, for optimal absorption.

Where does your fisetin come from?

Our fisetin is naturally extracted from the smoke tree (Cotinus coggygria), one of the richest natural sources, rather than synthesised. Every batch is third-party tested, with the current batch at 100% purity, and our capsules are made in the UK to GMP standards.

What is fisetin and what are its benefits?

How long do I need to supplement for to achieve the benefits?

What is a senolytic, and why does it matter?

Every single batch is tested by third-party labs.

Batch tested for heavy metals, toxins, and unwanted contaminants. Nothing gets shipped unless it meets the highest safety standards.

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Some of the reviews shown are from related products the merchant grouped with this one.

Really happy with my Manapura Pure Fisetin, feeling great.

The website was easy to navigate and delivery very quick. After using Fisetin consistently, I noticed steady improvements over 12 weeks. I also had some questions around the science which was communicated by someone who clearly knew what they were talking about. Great product and customer service.

Other similar products ive bought came in a plastic tub in a brown box. This packaging is second to none

Taking Fisetin with Spermidine. Feeling less inflammation for sure.

Reducing inflammation very quickly. Highly recommend this product!

High dose, great stuff

Pure Fisetin

Bought this as part of the trio, I'll admit I read about the use cases of Fisetin after ordering but now very excited to try, if my body needs anything right now it's a thorough cleaning 😂

Pure Fisetin

Heard Huberman talk about the benefits of Fisetin supplements on his podcast and hadn't tried them before but after reading more studies I'd recommend anyone over 30 using these.

Pure Fisetin

Manapura Spermidine offers a solid dose at a fair price. After a few weeks, I've noticed clearer focus and steady energy. Knowing it supports autophagy and healthy ageing makes it feel like a smart, well-formulated addition to my routine. No side effects so far.

Pure Fisetin

Heard about Fisetin from Huberman and started taking about a year ago - powerful stuff, recommend if you're into the anti-aging world. Hadn't seen a UK brand make this well so was ordering from America but very happy to stick with this one now - quality stuff.

Pure Fisetin

This fisetin is great value for the quality. I used to take Chavara but much prefer this brand - after a few weeks, I feel more focused and clear-headed. Knowing it's been properly tested gives me confidence I'm taking something safe and effective for brain health and ageing well.

Pure Fisetin

I've been taking fisetin for roughly a year since my mum was diagnosed with Alzhiemers read that fisetin can help with prevention of chronic diseases by being an anti-inflammatory. In any case, I totally vouch for it as a supplement for energy and focus, I just swapped to the Manapura one as my old brand only did 250mg and these are 400mg per capsule.

Also - the packaging is much more chic.

Pure Fisetin

Ive tried a few Fisetin brands from the US, but Manapura's feels cleaner and more bioavailable. Noticeable anti-infammatory benefits and way more energy. Highly recommend!

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert