60 Servings
GMP Cert.
3rd Party Tested

Pure Berberine ∘ 500mg per serving

Blood Sugar
Metabolism
Heart Health

Pure Berberine to stabilise your blood sugar and restore steady energy

Free quick delivery worldwide

Accreditations

Ultra pure, high-grade ingredients only Naturally sourcedClinical-strength daily doseMicronised for maximum absorbencyLab-grade, UV safe amber glass vessel
 

✓ Regulate Blood Sugar

✓ Supports Healthy Weight Management

✓ Improves Heart Health

✓ Boosts Gut Health

✓ Fights Inflammation & Oxidative Stress

Daily supplementation over 12 weeks has been shown to have significant effects on blood glucose levels, as well as improved lipid biomarkers.

Contains 60 capsules. One capsule contains 500mg of pure Berberine, naturally sourced from Berberis Aristata plant extract.

The capsule shell is made from 100% vegetable cellulose.

  • Vegan and Vegetarian
  • Gluten Free
  • Non-GMO
  • Allergen Free
  • Halal / Kosher Friendly

For maximum effectiveness, take one capsule up to three times per day with a meal for optimal absorption.

Berberine can be taken at any time of day; however, taking it at the same time every day is recommended.

This product is intended for use by healthy adults only. Do not take if you are pregnant or breastfeeding.

For best results, complement your supplement routine with a balanced diet. Always consult with your doctor or healthcare professional before beginning any supplement, and never exceed the recommended daily dose.

UK ORDERS:

  • Standard Delivery (FREE):Delivered via Royal Mail 48H service.
  • Express Delivery (£3.95): Delivered via Royal Mail 24H service..

INTERNATIONAL ORDERS:

  • Standard Delivery (FREE): Delivered via Fedex Economy Services, 3-7 days.
  • Express Delivery (£3.95): Delivered via Fedex Prioirty Services, 2-4 days.

We are proud to cover customs, duties and taxes for our international customers.

Manapura delivers the purest Berberine available, naturally extracted and rigorously tested for your peace of mind.

Clinically studied to activate AMPK, supporting fat utilisation, glucose balance, body composition, and longevity.

Ultra Pure

Extracted naturally - with absolutely no synthetic additives or fillers

Medical Grade

We make our supplements in certified facilities (cGMP & ISO 9001) the same standards used for best-in-class pharmaceuticals.

Micronised For Maximum Absorption

Our formulas are processed into tiny particles (micronised) so your body can absorb it more easily.

Vegan & Gluten-Free

Purposefully suitable for most diets, our zero-tolerance for additives gives you the cleanest form that the body recognises and can absorb.

Manapura® VS Most Brands On The Market

Pure Berberine Supplement FAQs

What is Berberine, and how does it benefit metabolism?

Berberine is a natural compound that can support blood sugar, weight management, and cardiovascular wellness.

How long do I need to supplement for to achieve the benefits?

Daily supplementation over 12 weeks has been shown to have significant effects on blood glucose levels, as well as improved lipid biomarkers.

Can I take Berberine with other blood sugar and blood pressure medications?

Berberine may interact with medications for blood sugar, and blood pressure. Always consult your healthcare provider before combining it with prescriptions.

What’s the optimal daily dosage of Berberine?

The most studied dosage is 500 mg, 2–3 times per day (totaling 1000–1500 mg/day), split between meals for best results.

How should I take Berberine?

Take 1 capsule up to 3 times daily with meals for the best absorption and effectiveness.

What is Berberine, and how does it benefit metabolism?
How long do I need to supplement for to achieve the benefits?
Can Berberine help with weight loss?
Can I take Berberine with other blood sugar and blood pressure medications?
What’s the optimal daily dosage of Berberine?
How should I take Berberine?

Every single batch is tested by third-party labs.

Batch tested for heavy metals, toxins, and unwanted contaminants. Nothing gets shipped unless it meets the highest safety standards.

  • 5 stars: 22 (100%)
  • 4 stars: 0 (0%)
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  • 1 star: 0 (0%)
Some of the reviews shown are from related products the merchant grouped with this one.
L
Liberty

My eldest actually got me on to this for hair regrowth. It’s working well for both of us. I knew about its benefits for for cholesterol and anti inflammatory but not hair.

A
Anonymous

Really noticing a difference on this product.

J
Jonathan

What impressed me is the quality of the product and customer service. The packaging is also lovely and arrived securely packed with the communication very clear.

R
Raymond

Have lost 6kg in the last month

J
Jimmy

Slick packaging and quick delivery. Very pure berberine

H
Holly A.

Nice packaging, quick delivery

K
Kim R.

Already noticed that I've lost weight since taking these 2 weeks ago

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Jess D.

Obsessed with Berberine for helping manage PCOS - it's all I take now instead of Inositol.

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Louise B.
Pure Berberine

Super quick delivery, and its a nice touch that this sits pretty in my bathroom!

B
Ben M.
Pure Berberine

Glad it's a UK brand - would recommend

K
Kieran B.
Pure Berberine

Fast delivery, thank you. Will repurchase once I get through it all - rather shop from a UK brand

J
James P.
Natural Spermidine

Came quick and nice packaging, will buy again when this runs out

K
Kimberley S.
Purest Berberine

I'm 29 and was recently advised to look into support for my PCOS, I did a lot of research and came across several studies comparing Berberine to Memformin, and so gave Berberine a try. I chose Manapura because purity and third-party testing are non-negotiables for me, especially with supplements. After a couple of months, I've noticed much higher energy throughout the day and less of that post-carb crash that my fellow PCOS girlies will know well!! I also appreciate that it feels like a more natural alternative without having to rely on medication at my age.

D
Dominic P.
Pure Berberine

I'm 30 and started taking berberine after hearing it could support blood sugar balance and make it easier to maintain a healthy weight. I've always struggled with sugar cravings and energy dips in the afternoon, but within a couple of weeks I noticed they were much less intense.

I like that berberine is a natural supplement with a lot of research behind it. The capsules are easy to take and I haven't had any side effects.

H
Hannah K.
Pure Berberine

I started looking into berberine as a natural substitute for metformin after experiencing side effects with it. I found this one on pinterest - what I wanted was something clean, just pure berberine.

If you have PCOS I recommend trying it - I notice more stable energy levels and better blood sugar balance, especially post-meal. For anyone looking at an alternative to metformin, this is worth a go.

H
Hannah K.
Natural Spermidine

Bought this as part of the Cellular Renewal Set as I needed Berberine + Fisetin anyway, but since taking Spermidine I've really noticed my hair feeling much healthier and softer, not sure if it's as a result of taking them all in tandem but I'll take it!

T
Tommy T.
Pure Berberine

i have been using berberine in different doseages for a number of years, i think this one is good

J
James H.
Pure Berberine

Ultra pure Berberine. Can really tell the difference. Definetely helping to manage blood sugar and weight control.

J
James H.
Natural Spermidine

Been taking the Manapura Spermidine for 3 weeks and my hair and skin are noticeably healthier. I'm using this as part of my longevity protocol, and this feels liike a bit of a secret weapon.

J
James H.
Natural Spermidine

Been taking the Manapura Spermidine for 3 weeks and my hair and skin are noticeably healthier. I'm using this as part of my longevity protocol, and this feels liike a bit of a secret weapon.

K
Kate
Pure Berberine

I've switched to Manapura Berberine after using Metformin alternatives, and this is the real deal. Energy is up, sugar cravings are down. You can tell it's high-grade, with no unnecessary binders.

K
Kate
Pure Berberine

I've switched to Manapura Berberine after using blood sugar support alternatives, and this is the real deal. Energy is up, sugar cravings are down. You can tell it's high-grade, with no unnecessary binders.

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Meet our Advisors

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

READ INTERVIEW

Dr. Cherry Lo, Ph.D., is a researcher specialising in pathology and immunity, with degrees from CUHK and the University of Hong Kong. Her work focuses on the interaction between NK cells and rheumatoid arthritis, providing new insights into disease mechanisms. As a research scientist, she contributes to advancements in longevity science. With a passion for immunology and translational research, Dr. Lo is dedicated to uncovering innovative solutions for age-related diseases and immune health.

DR. CHERRY LO, Ph.D

Longevity Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Ben is the founder and head grower at one of the UK’s leading fungi farms, where he cultivates a deep passion for mushroom cultivation and education. Since launching his farm in 2022, he has dedicated himself to exploring fungi’s medicinal and ecological potential. Ben is a regular speaker at functional mushroom conferences around the UK where he shares his knowledge and enthusiasm for the fungal kingdom. He aims to inspire others to connect with these fascinating organisms.

BEN GIBSON

Mycology Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert

Carolina is a holistic sleep coach specialising in circadian biology, nutritional therapy, and biohacking. With over seven years of experience, she blends scientific research with ancestral wisdom to help clients achieve deep, restorative sleep naturally. Her expertise in light exposure, stress resilience, and nervous system regulation allows her to create personalised, sustainable solutions without reliance on medication. Carolina is passionate about empowering individuals to optimise their sleep and overall well-being through evidence-based, holistic practices.

CAROLINA RAMUSKI

Sleep Expert